Liu Wei Di Huang Wan六味地黄丸
Six-Ingredient Pill with Rehmannia (Rehmannia Six Formula)
Ingredients6 herbs
Indications
Kidney yin deficiency, frequently involving the Liver: essence and yin fail to fill the lower source, deficiency heat stirs from within, and the sensory orifices and sinew-bone lose their nourishment. Practitioners commonly consider it for chronic presentations conforming to this pattern — pattern first, disease name second.
Clinical Manifestations
- Soreness and weakness of the lower back and knees
- Dizziness, tinnitus, diminished hearing
- Night sweats, steaming-bone sensations, heat in palms and soles
- Chronic yin-deficiency presentations in endocrine and geriatric contexts
Health Categories
Modern Applications
Common adjustments
- Pronounced deficiency fire — add Zhi Mu 知母, Huang Bai 黄柏 — Zhi Bai Di Huang Wan 知柏地黄丸
- Blurred or dry eyes — add Gou Qi Zi 枸杞子, Ju Hua 菊花 — Qi Ju Di Huang Wan 杞菊地黄丸
- Lung–Kidney yin deficiency with cough — add Mai Dong, Wu Wei Zi 五味子 — Mai Wei Di Huang Wan 麦味地黄丸
Contraindications
The chief herb is rich and cloying: use carefully where Spleen deficiency shows as poor appetite or loose stools. Not appropriate for yang-deficiency presentations.
For licensed practitioners’ reference only — not a self-treatment guide.
Pregnancy
Generally compatible — practitioner judgment applies
Related Formulas
References
Source Xiao Er Yao Zheng Zhi Jue 《小儿药证直诀》 · Northern Song dynasty
「地黄丸：治肾怯失音，囟开不合，神不足，目中白睛多，面色㿠白等方。」
- Qian Yi 钱乙. Xiao Er Yao Zheng Zhi Jue《小儿药证直诀》(classical source).
2. Scheid, Bensky, Ellis & Barolet. Chinese Herbal Medicine: Formulas & Strategies, 2nd ed. — composition & dosage cross-checked.
3. 《方剂学》（规划教材）— pattern analysis cross-checked.
Professional reference notice. Entries are scholarly references for licensed TCM practitioners and students — not medical advice, and not a recommendation to self-prescribe. Chinese herbal formulas should be used under the guidance of a qualified practitioner. Content is an original editorial compilation by Cura x Cura, cross-checked against the cited references.