Long Dan Xie Gan Tang龙胆泻肝汤
Gentian Decoction to Drain the Liver (Gentiana Combination)
Ingredients10 herbs
Indications
Liver–Gallbladder excess fire flaring upward together with Liver-channel damp-heat pouring downward. The two halves of the picture are one excess taking two routes, which is why a single formula addresses both ends.
Clinical Manifestations
- Splitting headache with red eyes, tinnitus or sudden hearing loss
- Bitter taste, irritability and hypochondriac pain
- Burning, urgent, turbid or bloody urination
- Genital swelling, itching, sweating or foul yellow discharge
- Damp-heat eruptions along the Liver channel, such as shingles presentations
Health Categories
Modern Applications
Common adjustments
- Fire predominant — pounding headache, red eyes — increase Long Dan Cao 龙胆草; add Ju Hua 菊花, Xia Ku Cao 夏枯草
- Damp-heat predominant below — increase Che Qian Zi 车前子; add Tu Fu Ling 土茯苓, Bi Xie 萆薢
- Constipation accompanying the fire — add Da Huang 大黄 for a short course only
- Shingles-type eruption along the channel — add Ban Lan Gen 板蓝根, Da Qing Ye 大青叶
- Spleen already weak, loose stools appearing — reduce the bitter cold herbs, add Spleen-protecting herbs, and shorten the course
Contraindications
Strongly bitter and cold — for a confirmed excess pattern only, and only for as long as the excess lasts, since prolonged use injures the middle burner. Not for Spleen–Stomach deficiency with loose stools and poor appetite, and not for the yin-deficiency fire that resembles it but shows a thin rapid pulse and a peeled tongue. One ingredient needs checking: Mu Tong must be the Clematis-derived Chuan Mu Tong, or a substitute such as Tong Cao 通草. The Aristolochia-derived Guan Mu Tong contains aristolochic acid, has caused severe kidney injury, and is banned — practitioners should confirm the botanical source on any product label.
For licensed practitioners’ reference only — not a self-treatment guide.
Pregnancy
Contraindicated in pregnancy — the formula is strongly bitter and cold and drives damp-heat downward through the urine, which is not appropriate during pregnancy.
Related Formulas
References
Source Yi Fang Ji Jie 《医方集解》 · Qing dynasty
「治肝胆经实火湿热,胁痛耳聋,胆溢口苦,筋痿阴汗,阴肿阴痛,白浊溲血。」
- Classical source (public domain), cited in the source-quote section.
2. Scheid, Bensky, Ellis & Barolet. Chinese Herbal Medicine: Formulas & Strategies, 2nd ed. — composition & dosage cross-checked.
3. 《方剂学》(全国中医药行业高等教育规划教材)— pattern analysis cross-checked.
Professional reference notice. Entries are scholarly references for licensed TCM practitioners and students — not medical advice, and not a recommendation to self-prescribe. Chinese herbal formulas should be used under the guidance of a qualified practitioner. Content is an original editorial compilation by Cura x Cura, cross-checked against the cited references.
